Using the ventus in Laser Tweezers Raman Spectroscopy (LTRS)
Unfortunately, one in two people born after 1960 in the UK will be diagnosed with some form of cancer during their lifetime. Typical large-scale analysis of cancer cells means individual cell attributes are averaged and, therefore, single cell detection is of real interest. The current process involves individual analysis of manually trapped cells which is time-consuming but this process has recently become automated by Laser Tweezer Raman Spectroscopy (LTRS) as shown in recent studies: Automated analysis of single cells using Laser Tweezer Raman Spectroscopy. The technique uses a Diode Pumped Solid State (DPSS) ventus 1064 nm laser, which has a maximum power output of 1.5 W, reduced at the sample plane to 250 mW and a single mode (TEM00) beam as required for efficient trapping. The ventus also has an M2 of less than 1.5, which enables effective and competent trapping. The low-cost technique, which introduces a microfluidic flow chamber, has greatly reduced the level of operator input required thus reducing the time involved in the process whilst supplying invaluable cellular data. To learn more about this technique, download our latest whitepaper.